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References Vitamin B Complex Treatment Attenuates Local Inflammation after Peripheral Nerve Injury Peripheral nerve injury (PNI) triggers different cellular and molecular events crucial for axon regeneration and tissue reinnervation and inflammation is one of these processes

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In animal-model work, NNMT inhibition with 5-Amino-1MQ has been associated with changes in adipose-tissue mass, in NAD+ pool sizes (because NNMT consumes nicotinamide that would otherwise feed the NAD+ salvage pathway), and in methyl-donor dynamics (because NNMT consumes S-adenosylmethionine)